 Progesterone is not the same as Progestin (a synthetic form of progesterone). Progestin's (also known as Medroxyprogesterone Acetate) are not biologically identical to natural progesterone due to their chemical alteration. Because they are not the same drug, synthetic progestins do not share the positive actions of natural Progesterone. Similarly, natural Progesterone does not share the negative side effects of synthetic progestins.
Progesterone is a potent intracellular metabolite
Progesterone is a neurological relaxant that may help reduce the frequency and intensity of migraines. Progesterone is needed by GABA receptors in the brain and to balance the effects of estrogen. Short term exposure to progesterone stimulates tissue and prolonged exposure causes cells to mature and differentiate. There are also numerous benefits for the cardiovascular system. If progesterone is not balanced with estrogen, it may raise blood sugar and put one at risk for diabetes. Balance is the key in hormone therapy.
High progesterone
Excess progesterone may cause any of the following symptoms:
- Gastrointestinal Bloating
- Mild Depression
- Candida occurrences
- Breast Swelling
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- Somnolence (sleepiness)
- Increased symptoms of estrogen deficiency
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Low progesterone
The following are some of the symptoms of progesterone deficiency:
- Anxiety
- Foggy Thinking
- Forgetfulness
- Acne
- Low libido
- Depression
- Irritability
- Tender/swollen breasts
- Water retention
- Weight gain at the hips
- Headaches
- Migraines
- Premenstrual Syndrome (PMS)
- Excessive menstruation
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- Irregular periods
- Cramping
- Infertility
- Hypothyroid symptoms (fatigue, weight gain, hair loss, feeling cold, constipation, dry skin)
- Mood swings
- Insomnia
- Pain and inflammation
- Joint pain
- Bone loss
- Sleep disturbances
- Decreased high-density lipoprotein (HDL)
- Increased symptoms of estrogen dominance
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